KDEL receptor 1; ER lumen protein retaining receptor 1; KDEL endoplasmic reticulum protein retention receptor 1; MAPK-activating protein PM23 (KDELR1, ERD21)

Function

• required for retention of luminal endoplasmic reticulum proteins
• determines the specificity of the luminal ER protein retention system
• also required for normal vesicular traffic through Golgi
• recognizes K-D-E-L (KDEL motif)
• interacts with ARFGAP1 (putative)

Structure

belongs to the ERD2 family

Compartment

endoplasmic reticulum membrane

More general terms

• KDEL receptor (ER lumen protein-retaining receptor)

Additional terms

• endoplasmic reticulum (ER)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1094
• OMIM: https://mirror.omim.org/entry/131235
• UniProt: http://www.uniprot.org/uniprot/P24390.html