Rho GTPase-activating protein 12; Rho-type GTPase-activating protein 12 (ARHGAP12)

Function

• GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (putative)

Structure

• contains 1 PH domain
• contains 1 Rho-GAP domain
• contains 1 SH3 domain
• contains 2 WW domains

Alternative splicing

named isoforms=3

More general terms

• rho GTPase-activating protein (rho-GAP)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=94134
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:94134
• OMIM: https://mirror.omim.org/entry/610577
• UniProt: http://www.uniprot.org/uniprot/Q8IWW6.html