far upstream element-binding protein 3; FUSE-binding protein 3 (FUBP3, FBP3)

Function

• may interact with single-stranded DNA from the far-upstream element (FUSE)
• may activate gene expression
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

contains 4 KH domains

Compartment

nucleus (probable)

Alternative splicing

named isoforms=2

Expression

detected in a number of cell lines

More general terms

• Far upstream element binding protein (FUSE binding protein)
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8939
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8939
• OMIM: https://mirror.omim.org/entry/603536
• UniProt: http://www.uniprot.org/uniprot/Q96I24.html