transcription factor Sp4; stimulatory protein 4 (Sp4, SPR-4)

Function

• binds to GT & GC boxes promoters elements
• probable transcriptional activator

Structure

• belongs to the Sp1 C2H2-type Zn+2-finger protein family
• contains 3 C2H2-type Zn+2 fingers

Compartment

nucleus

Expression

abundant in brain

More general terms

• Sp1 transcription factor family
• C2H2 type zinc finger protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6671
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6671
• OMIM: https://mirror.omim.org/entry/600540
• UniProt: http://www.uniprot.org/uniprot/Q02446.html