transcription factor EB (TFEB)
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Function
- probable transcription factor
- binds to the USF/MLTF site & probably recognizes E-box sequences in the heavy-chain immunoglobulin enhancer
- efficient DNA binding requires dimerization with another bHLH protein
Structure
- belongs to the MiT/TFE family
- contains 1 basic helix-loop-helix (bHLH) domain
Compartment
Alternative splicing
named isoforms=2
More general terms
References
- ↑ Ross CA, McInnis MG, Margolis RL, Li SH. Genes with triplet repeats: candidate mediators of neuropsychiatric disorders. Trends Neurosci. 1993 Jul;16(7):254-60. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7689767
- ↑ Atlas of genetics & cytogenetics in oncology & haematology http://atlasgeneticsoncology.org/genes/TFEBID531.html
- ↑ UniProt http://www.uniprot.org/uniprot/P19484.html