phospholipid-transporting ATPase 1G; ATPase IQ; ATPase class 6 type 11C (ATP11C, ATPIG, ATPIQ)

Function

• role in the transport of phospholipids from the outer to the inner leaflet of various membranes & the maintenance of asymmetric distribution of phospholipids
• phosphorylated upon DNA damage, probably by ATM or ATR

ATP + H2O + phospholipid(In) = ADP + phosphate + phospholipid(out)

Structure

• belongs to the cation transport ATPase (P-type) (TC 3.A.3) family, type IV subfamily

Compartment

membrane

Alternative splicing

named isoforms=4

Expression

widely expressed

More general terms

• phospholipid-transporting ATPase
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=286410
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:286410
• OMIM: https://mirror.omim.org/entry/300516
• UniProt: http://www.uniprot.org/uniprot/Q8NB49.html