ATP-binding cassette sub-family C member 12 (ATP-binding cassette C12, multidrug resistance-associated protein 9, ATP-binding cassette transporter sub-family C member 12, ABCC12, MRP9)

Function

• transporter (putative)

Structure

• belongs to the ABC transporter family, conjugate transporter (TC 3.A.1.208) subfamily
• contains 2 ABC transmembrane type-1 domains contains 2 ABC transporter domains

Compartment

membrane

Alternative splicing

named isoforms=5

Expression

• expressed in testis
• widely expressed at low level
• isoform 5 is specifically expressed in brain, testis
• expressed in fetal tissues

Pathology

• isoform 5 is expressed in breast cancer cells

More general terms

• P-glycoprotein (gp170) or multidrug-resistance glycoprotein
• ATP-binding cassette sub-family C (ABC transporter-C, ABCC)
• transmembrane 10 protein

Database

• OMIM: https://mirror.omim.org/entry/607041
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=94160
• UniProt: http://www.uniprot.org/uniprot/Q96J65.html