ubiquitin-conjugating enzyme E2 G2; ubiquitin carrier protein G2; ubiquitin-protein ligase G2 (UBE2G2)

Function

• accepts ubiquitin from the E1 complex & catalyzes its covalent attachment to other proteins
• in vitro catalyzes Lys-48-linked polyubiquitination
• involved in endoplasmic reticulum-associated degradation (ERAD)
• protein modification; protein ubiquitination

Structure

• belongs to the ubiquitin-conjugating enzyme family

More general terms

• ubiquitin-conjugating protein E2 (ubiquitin carrier protein)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7327
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7327
• OMIM: https://mirror.omim.org/entry/603124
• UniProt: http://www.uniprot.org/uniprot/P60604.html