rabphilin-3A; exophilin-1 (RPH3A, KIAA0985)

Function

• protein transport
• probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic &/or synaptic vesicle fusion.
• role in neurotransmitter release by regulating membrane flow in the nerve terminal (putative)

Structure

• contains 2 C2 domains
• contains 1 FYVE-type Zn+2 finger
• contains 1 RabBD (Rab-binding) domain

Compartment

cell junction, synapse (putative)

Alternative splicing

named isoforms=2

More general terms

• plasma membrane protein
• Ca+2 binding protein
• phosphoprotein
• zinc finger protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=22895
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:22895
• UniProt: http://www.uniprot.org/uniprot/Q9Y2J0.html