DNA-directed RNA polymerase 1 associated factor 53 kD subunit (PAF53)

Function

• component of RNA polymerase 1
• appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between RNA polymerase 1 & UBTF/UBF (putative)
• interacts with PAF49/CD3EAP
• also binds UBTF/UBF (putative)

Structure

• belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family

Compartment

nucleus, nucleolus

Alternative splicing

named isoforms=2

More general terms

• protein subunit

Component of

• RNA polymerase 1

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6442
• UniProt: http://www.uniprot.org/uniprot/Q9GZS1.html