alcohol dehydrogenase [ADH]-1

Function

• serves to remove ethanol formed by intestinal flora
• substrate specificity: broad

an alcohol + NAD+ <--> an aldehyde or ketone + NADH

Structure

• dimer of identical or non-identical chains of 3 types ADH-alpha, ADH-beta, ADH-gamma

Expression

ADH-alpha primarily active in early fetal life

More general terms

• alcohol dehydrogenase (aldehyde reductase)
• oligomerizing protein

Additional terms

• alcohol dehydrogenase 1A (alcohol dehydrogenase subunit alpha, ADH1A, ADH1)

Database

• OMIM: https://mirror.omim.org/entry/103700