K+ channel subfamily K member 17; TWIK-related alkaline pH-activated K+ channel 2; 2P domain K+ channel Talk-2; TWIK-related acid-sensitive K+ channel 4; TASK-4 (KCNK17 TALK2, TASK4, UNQ5816/PRO19634)

Function

• outwardly-rectifying K+ channel
• produces rapidly activating & non-inactivating outward rectifier K+ currents

Structure

• homodimer (putative)
• belongs to the two pore domain K+ channel (TC 1.A.1.8) family

Compartment

membrane

Notes

• inhibited by Ba+2, quinidine, chloroform & halothane
• activated at alkaline pH
• activated by quinine & isoflurane

More general terms

• K+ channel subfamily K
• transmembrane 4 protein
• glycoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=89822
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:89822
• OMIM: https://mirror.omim.org/entry/607370
• UniProt: http://www.uniprot.org/uniprot/Q96T54.html