K+ channel subfamily K member 15; acid-sensitive K+ channel protein TASK-5; TWIK-related acid-sensitive K+ channel 5; Two pore K+ channel KT3.3 (KCNK15, TASK5)

Function

• probable K+ channel subunit
• no channel activity observed in heterologous systems
• may need to associate with another protein to form a functional channel
• heterodimer (putative)

Structure

• belongs to the two pore domain K+ channel (TC 1.A.1.8) family

Compartment

membrane

Expression

• detected in pancreas, heart, placenta, lung, liver, kidney, ovary, testis, skeletal muscle & adrenal gland
• expressed in lower levels in prostate, spleen & thyroid gland

Polymorphism

• 3 variant polypeptides are known: TASK-5A, TASK-5B & TASK-5C

More general terms

• K+ channel subfamily K
• transmembrane 4 protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=60598
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:60598
• OMIM: https://mirror.omim.org/entry/607368
• UniProt: http://www.uniprot.org/uniprot/Q9H427.html