monocarboxylate transporter 4; MCT 4; solute carrier family 16 member 3 (SLC16A3, MCT4)
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Function
- proton-linked monocarboxylate transporter
- catalyzes rapid transport across the plasma membrane of many monocarboxylates including:
- lactate
- pyruvate
- branched-chain oxo acids derived from leucine, valine & isoleucine
- ketone bodies
Structure
- belongs to the major facilitator superfamily monocarboxylate porter (TC 2.A.1.13) family
Compartment
Expression
highly expressed in skeletal muscle