cystatin 7, cystatin-F, leukostatin or cystatin-like metastasis-associated protein (CMAP)

Function

• inhibits papain & cathepsin L, but with affinities lower than other cystatins
• may play a role in immune regulation through inhibition of a unique target in the hematopoietic system

Structure

• homodimer, disulfide-linked
• belongs to the cystatin family

Compartment

secreted, cytoplasm

Expression

• primarily expressed in peripheral blood cells & spleen

More general terms

• cystatin

Database

• UniProt: http://www.uniprot.org/uniprot/O76096.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8530
• OMIM: https://mirror.omim.org/entry/603253
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8530