interferon [IFN]-alpha 4; IFN-alpha 4B; IFN-alpha M1; IFN-alpha 76 (IFNA4)

Function

• antiviral activities
• stimulates the production of two enzymes:
  • a protein kinase
  • an oligoadenylate synthetase

Structure

belongs to the alpha/beta interferon family

Compartment

secreted

Expression

• expressed & secreted by macrophages

Polymorphism

• two forms exist; IFN alpha-4a & IFN alpha-4b
• they seem to be equally abundant

More general terms

• interferon [IFN]-alpha

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3441
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3441
• OMIM: https://mirror.omim.org/entry/147564
• UniProt: http://www.uniprot.org/uniprot/P05014.html