interferon [IFN]-alpha 1; IFN-alpha 13; IFN-alpha D; LEIF D (IFNA1)

Function

• antiviral activities
• stimulates the production of two enzymes
  • a protein kinase
  • oligoadenylate synthetase

Structure

• belongs to the alpha/beta interferon family

Compartment

secreted

Expression

• expressed & secreted by macrophages

Polymorphism

Two forms exist; IFN alpha-1a & IFN alpha-1b

Notes

• IFN alpha-1 & IFN alpha-13 have identical protein sequences

More general terms

• interferon [IFN]-alpha

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3439
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3447
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3439
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3447
• OMIM: https://mirror.omim.org/entry/147578
• OMIM: https://mirror.omim.org/entry/147660
• UniProt: http://www.uniprot.org/uniprot/P01562.html