leukocyte immunoglobulin-like receptor subfamily A member 5; leukocyte immunoglobulin-like receptor 9; LIR-9; immunoglobulin-like transcript 11; ILT-11; CD85 antigen-like family member F; CD85f (LILRA5, ILT11, LILRB7, LIR9)

Function

• may play a role in triggering innate immune responses
• seems not play a role for any class I MHC antigens recognition

Structure

• contains 2 Ig-like C2-type domain (immunoglobulin-like)

Compartment

• isoforms 1 & 3: membrane, secreted
• isoforms 3 & 4: secreted

Alternative splicing

named isoforms=4

Expression

• expressed mostly in tissues of the hematopoietic system, including bone marrow, spleen, lymph node & peripheral leukocytes
• among leukocytes, monocytes & neutrophils express the highest level
• expressed in CD14+ monocytes, but not in T-cells, B-cells or natural killer (NK) cells (at protein level)

More general terms

• CD85 or leukocyte immunoglobulin-like receptor family protein

Database

• OMIM: https://mirror.omim.org/entry/606047
• UniProt: http://www.uniprot.org/uniprot/A6NI73.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=79166