leukocyte immunoglobulin-like receptor subfamily A member 4; immunoglobulin-like transcript 7; ILT-7; CD85 antigen-like family member G; CD85g (LILRA4, ILT7)

Function

• may act as receptor for class 1 MHC antigens
• ligand binding leads to the activation of eosinophils & to release of RNASE2, IL4 & LTC4

Structure

• contains 4 Ig-like C2-type domains (immunoglobulin-like)

Compartment

• membrane; single-pass type 1 membrane protein

Alternative splicing

named isoforms=2

Expression

• detected on eosinophils, neutrophils & monocytes

More general terms

• CD85 or leukocyte immunoglobulin-like receptor family protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23547
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:23547
• OMIM: https://mirror.omim.org/entry/607517
• UniProt: http://www.uniprot.org/uniprot/P59901.html