glutamine synthetase; glutamate ammonia ligase (GLUL, GLNS)
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Function
-..........-
ATP + L-glutamate + NH3 <--> ADP + phosphate + L-glutamine
Structure
- homooctamer
- belongs to the glutamine synthetase family
Compartment
Expression
- within the rat CNS, preferentially expressed in astrocytes
Pathology
- defects in GLUL are the cause of congenital systemic glutamine deficiency
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/P15104.html
- ↑ Thug I, Gouw A, Dizon P, Zhao L, Zhang H, Zawaideh R, Solovyeva A, Timiras PS Long-term effects of growth factors on neuroglia: proliferation, dedifferentiation and neurogenesis Aging: Mechanisms and Prevention 34th Annual Meeting of the American Aging Association June 3-6, 2005, Oakland CA
- ↑ Wikipedia; Note: glutamine synthetase entry http://en.wikipedia.org/wiki/glutamine_synthetase