guanine nucleotide exchange factor for Rab3A (Rab3A-interacting-like protein 1, Rabin3-like , RAB3IL1)

Function

• guanine nucleotide exchange factor (GEF) for Rab3A, a GTPase that regulates synaptic vesicle exocytosis (putative)
• interacts with Rab3A & IHPK1 through the coiled coil domain (competitive, IHPK1 kinase activity not required)

Structure

belongs to the SEC2 family

Alternative splicing

named isoforms=2

More general terms

• guanine nucleotide exchange factor

Database

• UniProt: http://www.uniprot.org/uniprot/Q8TBN0.html