Ras-GEF domain-containing family member 1B (GPI gamma-4, RASGEF1B, GPIG4)

Function

• guanine nucleotide exchange factor (GEF) for Ras family proteins (in vitro) (putative)

Structure

• contains 1 N-terminal Ras-GEF domain
• contains 1 Ras-GEF domain

Alternative splicing

named isoforms=3

Expression

• up-regulated in monocytes stimulated with T.cruzi GPI-anchored mucins or bacterial lipopolysaccharide

More general terms

• guanine nucleotide exchange factor

Database

• UniProt: http://www.uniprot.org/uniprot/Q0VAM2.html