ankyrin repeat domain-containing protein 27 (VPS9 domain-containing protein, ANKRD27)

Function

• Rab21 guanine nucleotide exchange factor (putative)
• regulates endosome dynamics (putative)
• interacts with RAB21 & RAB5, strong preference for RAB21

Structure

• contains 11 ANK repeats
• contains 1 VPS9 domain

Compartment

• cytoplasm
• mainly localized to early endosomes in perinuclear region

More general terms

• guanine nucleotide exchange factor
• ankyrin repeat domain protein (ANKRD)

Database

• UniProt: http://www.uniprot.org/uniprot/Q96NW4.html