Dedicator of cytokinesis protein 10; Zizimin-3 (DOCK10, KIAA0694, ZIZ3)

Function

• potential guanine nucleotide exchange factor (GEF)

Structure

• the DHR-2 domain may mediate some GEF activity
• belongs to the DOCK family
• contains 1 DHR-1 domain
• contains 1 DHR-2 domain
• contains 1 PH domain

Alternative splicing

named isoforms=2

Expression

expressed at low level in brain, lung

More general terms

• dedicator of cytokinesis protein (DOCK)
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=55619
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:55619
• OMIM: https://mirror.omim.org/entry/611518
• UniProt: http://www.uniprot.org/uniprot/Q96BY6.html