fibroblast growth factor receptor-like 1; FGF receptor-like protein 1; fibroblast growth factor receptor 5; FGFR-like protein; FGF homologous factor receptor (FGFRL1, FGFR5, FHFR, UNQ480/PRO943)
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Function
- negative effect on cell proliferation
- interacts with FGF2 with a low affinity
Structure
- contains 3 Ig-like C2-type domain (immunoglobulin-like)
Compartment
- plasma membrane (majority), Golgi, secretory vesicles
Expression
- expressed preferentially in cartilagenous tissues & pancreas
- highly expressed in the liver, kidney, heart, brain & skeletal muscle
- weakly expressed in the lung, small intestine & spleen