wnt3 proto-oncogene protein or int4 proto-oncogene protein

Function

• ligand for members of the frizzled family
• Wnt-3 & Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube (putative)
• interacts with PORCN (putative)

Structure

belongs to the Wnt family

Compartment

• secreted, extracellular space, extracellular matrix

Pathology

• defects in WNT3 are the cause of autosomal recessive tetra-amelia

More general terms

• wnt proto-oncogene protein or int proto-oncogene protein

Database

• UniProt: http://www.uniprot.org/uniprot/P56703.html
• OMIM: https://mirror.omim.org/entry/165330
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7473