Ras-like protein family member 11A (RASL11A)

Structure

• belongs to the small GTPase superfamily, Ras family
• contains 1 Miro domain

Expression

• widely expressed
• lowest levels observed in endothelial cells
• high levels found in colon tumor & normal colon tissue followed by small intestine, liver, jejunum, ileum, bladder & aorta
• down-regulated during development of THP-1 monocytes into macrophages
• down-regulated by TGFB1

Pathology

• down-regulated in prostate tumors compared to normal prostate tissue

More general terms

• ras subfamily protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q6T310.html