sprouty-related, EVH1 domain-containing protein 3 (Spred-3, SPRED3)

Function

• tyrosine kinase substrate
• inhibits growth-factor-mediated activation of MAP kinase
• interacts with Ras
• phosphorylated on Tyr

Structure

• contains 1 SPR (sprouty) domain
• contains 1 WH1 domain

Compartment

peripheral membrane

More general terms

• sprouty-related, EVH1 domain-containing protein(SPRED)

Database

• UniProt: http://www.uniprot.org/uniprot/Q2MJR0.html