Golgin subfamily B member 1; 372 kD Golgi complex-associated protein; GCP372; Giantin; macrogolgin (GOLGB1)

Function

• may participate in forming intercisternal cross-bridges of the Golgi complex
• interacts with PLK3

Structure

• homodimer; disulfide-linked

Compartment

• Golgi membrane; single-pass type 1 membrane protein

Pathology

• autoantigen in chronic rheumatoid arthritis & in Sjogren's syndrome

More general terms

• Golgin subfamily B (GOLGB)
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2804
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2804
• OMIM: https://mirror.omim.org/entry/602500
• UniProt: http://www.uniprot.org/uniprot/Q14789.html