Rack-1 protein

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[1]

Introduction

Rack1 inhibits Fyn phosphorylation of the NR2B subunit of the NMDA receptor via binding to one or both proteins. This diminishes receptor-mediated currents through the NMDA receptor.

More general terms

References

  1. ↑ Yaka R, Thornton C, Vagts AJ, Phamluong K, Bonci A, Ron D. NMDA receptor function is regulated by the inhibitory scaffolding protein, RACK1. Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5710-5. Epub 2002 Apr 9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11943848
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