signal-regulatory protein (SIRP)

Introduction

SIRP family members are immunoglobulin superfamily proteins interacting with tyrosine kinases. Members of the SIRP-alpha subfamily have a cytoplasmic SH2-binding domain; members of the SIRP-beta subfamily lack this cytoplasmic tail.

More general terms

• immunoglobulin superfamily protein
• plasma membrane protein

More specific terms

• signal-regulatory protein gamma; SIRP-gamma; CD172 antigen-like family member B; signal-regulatory protein beta-2; SIRP-b2; SIRP-beta-2; CD172g (SIRPG, SIRPB2)
• signal-regulatory protein-alpha (SIRP-alpha)
• signal-regulatory protein-beta (SIRP-beta)

Database

• OMIM: https://mirror.omim.org/entry/603889