protocadherin-1; protocadherin-42; PC42; cadherin-like protein 1 (PCDH1)

Function

• may be involved in cell-cell interaction processes & in cell adhesion

Structure

contains 7 cadherin domains

Compartment

• cell junction, cell membrane
• single-pass type 1 membrane protein (probable)
• found at cell-cell boundaries & probably at cell-matrix boundaries

Alternative splicing

named isoforms=3

Expression

• highly expressed in the brain & neuroglial cells
• highest expression in adults

Notes

• uncertain whether Met-1 or Met-23 is the initiator

More general terms

• protocadherin (PCDH)
• phosphoprotein

Additional terms

• cadherin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5097
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5097
• OMIM: https://mirror.omim.org/entry/603626
• UniProt: http://www.uniprot.org/uniprot/Q08174.html