taste receptor, type 2, member 45 (T2R45, G-protein coupled receptor 59, TAS2R45, GPR59)
Jump to navigation
Jump to search
Function
- perception of bitterness
- gustducin-linked
- senses chemical composition of GI content (putative)
- stimulates alpha gustducin (putative)
- PLC-beta-2
- gating of TRPM5
Structure
belongs to the G-protein coupled receptor T2R family
Compartment
membrane
Expression
- expressed in subsets of taste receptor cells of the tongue & palate epithelium, exclusively in gustducin-positive cells.