taste receptor, type 2, member 12 (T2R12, taste receptor type 2 member 26, T2R26, TAS2R12, TAS2R26)
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Function
- perception of bitterness
- gustducin-linked
- senses chemical composition of GI content (putative)
- stimulates alpha gustducin (putative)
- PLC-beta-2
- gating of TRPM5
Structure
belongs to the G-protein coupled receptor T2R family
Compartment
membrane
Expression
- expressed in subsets of taste receptor cells of the tongue & palate epithelium, exclusively in gustducin-positive cells.
Notes
- confirmation pending
- withdrawn from UniProt July 2012