taste receptor, type 2, member 1 (T2R1, taste receptor family B member 7, TRB7, TAS2R1)

Function

• perception of bitterness
• gustducin-linked
• sensing the chemical composition of the GI content
• stimulates alpha gustducin
• PLC-beta-2
• gating of TRPM5

Structure

belongs to the G-protein coupled receptor T2R family

Compartment

membrane

Expression

• expressed in subsets of taste receptor cells of tongue & palate epithelium, exclusively in gustducin-positive cells

More general terms

• taste receptor, type 2

Database

• OMIM: https://mirror.omim.org/entry/604796
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5083
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=50834
• UniProt: http://www.uniprot.org/uniprot/Q9NYW7.html