low density lipoprotein (LDL) receptor related protein (LRP) 10 (SP220, UNQ389/PRO724, MSTP087, LRP10)

Function

• probable receptor
• may play role in the internalization of lipophilic molecules &/or signal transduction
• may be involved in the uptake of lipoprotein APOE in liver (putative)

Structure

• belongs to the LDLR family
• contains 2 CUB domains
• contains 4 LDL-receptor class A domains

Compartment

• membrane, coated pit (putative)

Alternative splicing

named isoforms=2

Expression

• expressed in blood leukocytes, lung, placenta, small intestine, liver, kidney, spleen, thymus, colon, skeletal muscle & heart

More general terms

• low-density lipoprotein (LDL) receptor related protein (LRP)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2602
• OMIM: https://mirror.omim.org/entry/609921
• UniProt: http://www.uniprot.org/uniprot/Q7Z4F1.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4041