microfibrillar-associated protein 5; MFAP-5; MP25; microfibril-associated glycoprotein 2; MAGP-2 (MFAP5 MAGP2)

Function

• component of the elastin-associated microfibrils
• forms intermolecular disulfide bonds either with other MAGP-2 molecules or with other components of the microfibrils

Structure

• N-glycosylated & O-glycosylated
• O-glycosylated with core 1 glycan or possibly core 8 glycans
• O-glycan heterogeneity at Thr-54: hexhexNAc (major) & hexhexNAc + sulfate (minor)
• belongs to the MFAP family

Compartment

• secreted, extracellular space, extracellular matrix

More general terms

• microfibrillar associated protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8076
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8076
• OMIM: https://mirror.omim.org/entry/601103
• UniProt: http://www.uniprot.org/uniprot/Q13361.html