neurocan core protein; chondroitin sulfate proteoglycan 3 (NCAN CSPG3 NEUR)
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Function
- may modulate neuronal adhesion & neurite growth during development by binding to neural cell adhesion molecules (NG-CAM & N-CAM)
- chondroitin sulfate proteoglycan; binds to hyaluronic acid
Structure
- belongs to the aggrecan/versican proteoglycan family
- contains 1 C-type lectin domain
- contains 2 EGF-like domains
- contains 1 Ig-like V-type domain (immunoglobulin-like)
- contains 2 link domains
- contains 1 Sushi (CCP/SCR) domain
Expression
brain
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/O14594.html
- ↑ Functional glycomics gateway - glycan binding - Note: neurocan http://www.functionalglycomics.org/glycomics/GBPServlet?&operationtype=view&cbpId=cbp_hum_Ctlect_213