alkaline phosphatase, placental-like 2 (germ-cell alkaline phosphatase, NAGAO isozyme, GCAP, PLAP-like, ALP-1, ALPPL2, ALPPL)

Function

• alkaline phosphatase

phosphate monoester + H2O <--> alcohol + phosphate

Cofactor:

• binds 1 Mg+2 (putative) binds 2 Zn+2 (putative)

Structure

• homodimer
• belongs to the alkaline phosphatase family

Compartment

cell membrane, lipid-anchor, GPI-anchor

Expression

• trace amounts in the testis & thymus

Pathology

• elevated amounts in germ cell tumors

More general terms

• alkaline phosphatase
• glypiated protein

Database

• UniProt: http://www.uniprot.org/uniprot/P10696.html
• OMIM: https://mirror.omim.org/entry/171810
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=251