glycine receptor alpha-3

Function

• glycine receptor subunit

Structure

• N-terminal domain confers agonist & antagonist binding
• transmembrane domain 2 forms innert wall of the Cl- channel
• cytoplasmic loop is a determinant of channel inactivation

Pathology

• alpha subunit binds strychnine

More general terms

• glycine receptor alpha

Database

• OMIM: https://mirror.omim.org/entry/600421
• UniProt: http://www.uniprot.org/uniprot/O75311.html