alpha-2C adrenergic receptor; alpha-2C adrenoreceptor; alpha-2C adrenoceptor; alpha-2 adrenergic receptor subtype C4 (ADRA2C, ADRA2L2, ADRA2RL2)

Function

alpha-2 adrenergic receptor

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

Polymorphism

• the del322-325 variant has a significant loss of function; it is approximately 10 times more frequent in African- Americans compared with Caucasians (allele frequencies 0.381 versus 0.040)

More general terms

• glycoprotein
• alpha-2 adrenergic receptor

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:152
• OMIM: https://mirror.omim.org/entry/104250
• UniProt: http://www.uniprot.org/uniprot/P18825.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=152