four & a half LIM domains protein 2; FHL-2; LIM domain protein DRAL; skeletal muscle LIM-protein 3; SLIM-3 (FHL2, DRAL, SLIM3)

Function

• may function as a molecular transmitter linking various signaling pathways to transcriptional regulation
• negatively regulates the transcriptional repressor E4F1
• may function in cell growth
• interacts with ZNF638 & TTN/titin
• interacts with E4F1

Structure

• the third LIM Zn+2-binding mediates interaction with E4F1
• contains 4 LIM Zn+2-binding domains

Compartment

• cytoplasm, nucleus

Expression

• expressed in skeletal muscle & heart

More general terms

• LIM domain protein
• phosphoprotein
• zinc finger protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2274
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2274
• OMIM: https://mirror.omim.org/entry/602633
• UniProt: http://www.uniprot.org/uniprot/Q14192.html