polycomb group protein ASXL1 (additional sex combs-like protein 1, ASXL1, KIAA0978)
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Function
Structure
- belongs to the Asx family.
- contains 1 PHD-type zinc finger
- contains 1 LXXLL motif (Leu-Xaa-Xaa-Leu-Leu), which may be required for an association with nuclear receptors
Compartment
Alternative splicing
named isoforms=2
Expression
- widely expressed at low level
- expressed in heart, brain, skeletal muscle, placenta, pancreas, spleen, prostate, small intestine, colon, peripheral blood, leukocytes, bone marrow, fetal liver
- highly expressed in testes