muscleblind-like X-linked protein (muscleblind-like protein 3, Cys3His CCG1-required protein, protein HCHCR, MBNL3, CHCR, MBLX39, MBXL)

Function

• inhibits terminal muscle differentiation, acting at approximately the time of myogenin induction (putative)

Structure

contains 4 C3H1-type zinc fingers

Compartment

• nucleus, cytoplasm
• greater concentration in nucleus

Alternative splicing

named isoforms=4

Expression

highly expressed in the placenta

Pathology

• in myotonic dystrophy (1 & 2) colocalizes with nuclear foci of retained expanded-repeat transcripts

More general terms

• zinc finger protein

Database

• OMIM: https://mirror.omim.org/entry/300413
• UniProt: http://www.uniprot.org/uniprot/Q9NUK0.html