zinc finger protein 259; zinc finger protein ZPR1 (ZNF259, ZPR1)

Function

• may be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus
• binds to the EGF receptor & PDGF receptor
• binds to the elongation factor 1-alpha EF1A (putative)
• component of an import snRNP complex composed of KPNB1, SNUPN, SMN1 & ZNF259

Structure

belongs to the ZPR1 family

Compartment

• cytoplasm, nucleus, nucleolus
• translocates to the nucleolus after treatment with mitogens

More general terms

• zinc finger protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8882
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8882
• OMIM: https://mirror.omim.org/entry/603901
• UniProt: http://www.uniprot.org/uniprot/O75312.html