succinyl-CoA sunthetase betaA subunit (succinyl-CoA ligase [ADP-forming] beta-chain, SCS-betaA, ATP-specific succinyl-CoA synthetase beta subunit, renal carcinoma antigen NY-REN-39, SUCLA2)

Function

• succinyl-CoA sunthetase beta subunit
• carbohydrate metabolism; tricarboxylic acid cycle

Structure

• belongs to the succinate/malate CoA ligase beta subunit family
• contains 1 ATP-grasp domain

Compartment

mitochondria

Alternative splicing

named isoforms=2

Expression

widely expressed

Pathology

• defects in SUCLA2 are a cause of myopathic mitochondrial DNA depletion syndrome

More general terms

• succinyl-CoA sunthetase betaG subunit

Component of

• succinyl CoA synthetase (GDP-formining)

Database

• OMIM: https://mirror.omim.org/entry/603921
• UniProt: http://www.uniprot.org/uniprot/Q9P2R7.html