EP300-interacting inhibitor of differentiation 3 (EID-3, EID-1-like inhibitor of differentiation 3, E1A-like inhibitor of differentiation 3, EID3)

Function

• repressor of nuclear receptor-dependent transcription possibly by interfering with CREBBP-dependent coactivation
• may function as a coinhibitor of other CREBBP/EP300- dependent transcription factors
• interacts with the C-terminal region of CREBBP

Structure

belongs to the NSE4 family

Compartment

• nucleus, cytoplasm
• may shuttle between nucleus & cytoplasm

Expression

highly expressed in testis

More general terms

• EP300-interacting inhibitor of differentiation

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4938
• UniProt: http://www.uniprot.org/uniprot/Q8N140.html