kinetochore protein Spc25 (hSpc25, SPC25, SPBC25, AD024)

Function

• component of kinetochore-associated NDC80 complex
• required for kinetochore integrity & organization of stable microtubule binding sites in the outer plate of the kinetochore

Compartment

• nucleus, kinetochore
• localizes to kinetochores from late prophase to anaphase
• localizes specifically to the outer plate of kinetochore

More general terms

• kinetochore protein

Component of

• NDC80 complex

Database

• UniProt: http://www.uniprot.org/uniprot/Q9HBM1.html