DNA polymerase sigma; LAK-1; PAP-associated domain-containing protein 7; terminal uridylyltransferase 5; TUTase 5; Topoisomerase-related function protein 4-1; TRF4-1 (PAPD7, POLS, TRF4)

Function

• DNA polymerase
• probably involved in DNA repair
• may play a role in sister chromatid cohesion
• does not play a role in replication-dependent histone mRNA degradation

Cofactor: Mg+2 or Mn+2 (putative)

Structure

• belongs to the DNA polymerase type-B-like family
• contains 1 PAP-associated domain

Compartment

nucleus (probable)

More general terms

• DNA polymerase
• nuclear protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=11044
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:11044
• OMIM: https://mirror.omim.org/entry/605198
• UniProt: http://www.uniprot.org/uniprot/Q5XG87.html