forkhead box protein N3; checkpoint suppressor 1 (FOXN3, C14orf116, CHES1)

Function

• acts as a transcriptional repressor
• may be involved in DNA damage-inducible cell cycle arrests (checkpoints)
• interacts through its C-terminus with the C-terminus of SNW1/SKIP

Structure

• contains 1 fork-head DNA-binding domain

Compartment

• nucleus (probable)

Alternative splicing

• named isoforms=2

More general terms

• DNA-binding protein
• forkhead family transcription factor
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1112
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1112
• OMIM: https://mirror.omim.org/entry/602628
• UniProt: http://www.uniprot.org/uniprot/O00409.html